Jacque L Duncan Selected Research

Retinal Degeneration

10/2021	Retinal Degeneration Secondary to MERTK Mutations: Potential Candidate for Gene Therapy.
1/2020	Perspectives on Gene Therapy: Choroideremia Represents a Challenging Model for the Treatment of Other Inherited Retinal Degenerations.
10/2019	Influence of eye pigmentation on retinal degeneration in P23H and S334ter mutant rhodopsin transgenic rats.
1/2019	Cone Spacing Correlates With Retinal Thickness and Microperimetry in Patients With Inherited Retinal Degenerations.
1/2018	Phenotypic characterization of P23H and S334ter rhodopsin transgenic rat models of inherited retinal degeneration.
1/2018	Relationship Between Foveal Cone Structure and Visual Acuity Measured With Adaptive Optics Scanning Laser Ophthalmoscopy in Retinal Degeneration.
1/2018	High-resolution Imaging in Male Germ Cell-Associated Kinase (MAK)-related Retinal Degeneration.
12/2017	A mutation in IFT43 causes non-syndromic recessive retinal degeneration.
4/2017	Genetic analysis of 10 pedigrees with inherited retinal degeneration by exome sequencing and phenotype-genotype association.
10/2016	Five-Year Safety and Performance Results from the Argus II Retinal Prosthesis System Clinical Trial.

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Jacque L Duncan Research Topics

Disease

26	Retinal Degeneration 10/2021 - 06/2002
11	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2020 - 03/2007
5	Retinal Diseases 01/2021 - 05/2007
5	Macular Degeneration (Age-Related Maculopathy) 01/2021 - 04/2004
4	Disease Progression 01/2021 - 05/2011
4	Choroideremia 01/2020 - 03/2002
3	Retinal Dystrophies 01/2022 - 02/2003
3	Atrophy 01/2022 - 01/2004
3	Cone-Rod Dystrophies 12/2012 - 05/2007
2	Fibrosis (Cirrhosis) 01/2022 - 01/2016
2	Inflammation (Inflammations) 07/2021 - 01/2020
2	Geographic Atrophy 01/2020 - 11/2013
2	Telangiectasis (Telangiectasia) 01/2019 - 01/2015
2	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2014 - 01/2005
2	Scotoma (Scintillating Scotoma) 01/2013 - 01/2004
2	Acute zonal occult outer retinopathy 04/2012 - 12/2004
2	Neuropathy ataxia and retinitis pigmentosa 03/2011 - 04/2009
2	Choroidal Neovascularization 11/2004 - 04/2004
1	Infections 01/2022
1	Cone Dystrophy 01/2022
1	Epiretinal Membrane (Epiretinal Membranes) 07/2021
1	Chorioretinitis 07/2021
1	Toxoplasmosis 07/2021
1	Familial Exudative Vitreoretinopathies 05/2021
1	Hemorrhage 05/2021
1	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2019
1	Seizures (Absence Seizure) 12/2017
1	Cerebellar Ataxia (Dysmetria) 12/2017
1	Ataxia Telangiectasia (Louis Bar Syndrome) 12/2017
1	Intellectual Disability (Idiocy) 12/2017
1	Apraxias (Dyspraxia) 12/2017
1	Fucosidosis 12/2016
1	Low Vision (Subnormal Vision) 05/2016
1	Retinal Hemorrhage 01/2016
1	Optic Nerve Hypoplasia 01/2016
1	Hemorrhagic Stroke 01/2016
1	Hyperlipoproteinemia Type III (Broad Beta Disease) 10/2014
1	Hemangioblastoma 03/2014
1	Sporadic Creutzfeldt-Jakob Disease 12/2013
1	Night Blindness (Nyctalopia) 10/2012
1	Retinitis 05/2011
1	Cytomegalovirus Retinitis 05/2011
1	Usher Syndromes (Usher Syndrome) 04/2011
1	Mitochondrial Diseases (Mitochondrial Disease) 03/2011
1	Ataxia (Dyssynergia) 03/2011
1	Bardet-Biedl Syndrome (Syndrome, Bardet-Biedl) 07/2010
1	Vitelliform Macular Dystrophy 07/2009
1	Endophthalmitis (Ophthalmia) 02/2005
1	Cystic Fibrosis (Mucoviscidosis) 02/2005
1	Opportunistic Infections (Opportunistic Infection) 02/2005
1	Pantothenate Kinase-Associated Neurodegeneration (Hallervorden-Spatz Disease) 01/2005
1	Azoospermia 01/2005

Drug/Important Bio-Agent (IBA)

25	Retinaldehyde (Retinal)IBA 01/2022 - 01/2004
7	Ciliary Neurotrophic Factor (CNTF)IBA 01/2019 - 06/2002
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 08/2015
3	Rhodopsin (Visual Purple)IBA 01/2020 - 01/2018
3	Proteins (Proteins, Gene)FDA Link 12/2017 - 07/2009
3	Retinal Pigments (Pigments, Visual)IBA 01/2013 - 01/2004
2	c-Mer Tyrosine KinaseIBA 10/2021 - 02/2003
2	salicylhydroxamic acid (SHAM)IBA 08/2013 - 04/2011
2	PeripherinsIBA 03/2011 - 03/2007
2	Mitochondrial DNA (mtDNA)IBA 03/2011 - 04/2009
1	tyrosyltubulin ligaseIBA 01/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 07/2021
1	SteroidsIBA 07/2021
1	LipidsIBA 01/2021
1	GTP Phosphohydrolases (GTPases)IBA 01/2020
1	Phosphotransferases (Kinase)IBA 01/2018
1	Codon (Codons)IBA 01/2018
1	Proline (L-Proline)FDA Link 01/2018
1	Histidine (L-Histidine)FDA Link 01/2018
1	DNA (Deoxyribonucleic Acid)IBA 04/2017
1	EnzymesIBA 12/2016
1	alpha-L-Fucosidase (Fucosidase)IBA 12/2016
1	Asparaginase (Elspar)FDA Link 01/2016
1	Apolipoproteins E (ApoE)IBA 10/2014
1	ApolipoproteinsIBA 10/2014
1	Quinacrine (Mepacrine)IBA 12/2013
1	Nonsense Codon (Nonsense Mutation)IBA 10/2012
1	LipofuscinIBA 05/2011
1	Adenosine Triphosphatases (ATPase)IBA 03/2011
1	ChaperoninsIBA 07/2010
1	Amino Acids FDA Link 07/2009
1	BestrophinsIBA 07/2009
1	Neuroprotective AgentsIBA 12/2007
1	pantothenate kinaseIBA 01/2005
1	Coenzyme A (CoA)IBA 01/2005
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 11/2004
1	Coloring Agents (Dyes)IBA 11/2004
1	Verteporfin (Visudyne)FDA Link 11/2004
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 04/2004

Therapy/Procedure

11	Lasers (Laser) 05/2021 - 11/2004
6	Therapeutics 07/2021 - 04/2004
3	Visual Prosthesis 10/2016 - 04/2012
1	Precision Medicine 01/2020
1	Aftercare (After-Treatment) 03/2017
1	Prostheses and Implants (Prosthesis) 03/2017
1	Highly Active Antiretroviral Therapy (HAART) 05/2011
1	Lung Transplantation 02/2005
1	Photochemotherapy (Photodynamic Therapy) 11/2004